The name Santiago is a combination of the Spanish word santo, meaning "saint," and the name Yago, an old Spanish form of James. Therefore, Santiago is the Spanish name for Saint James, the patron saint of Spain. Santiago has appeared in the Social Security Administration's top 1,000 for boy names every year since 1900, with the exception of 1905, but didn't crack the top-200 until 2007. It has now been a top-100 boy's name every year since 2017 and was the name actress Eva Longoria chose for her son Santiago Enrique, born in 2018.